CORONARY CYTOSKELETAL MODULATION OF CORONARY BLOOD FLOW IN THE PRESENCE AND ABSENCE OF TYPE 2 DIABETES: THE ROLE OF COFILIN

Coronary cytoskeletal modulation of coronary blood flow in the presence and absence of type 2 diabetes: the role of cofilin

BackgroundCoronary resistance microvessels (CRMs) from type 2 diabetic (T2DM) mice and pigs are less stiff compared to normal, a finding that is dictated by less stiff coronary vascular smooth muscle cells (VSMCs).Cofilin is an endogenous actin regulatory protein that depolymerizes filamentous (F)-actin, and portions of F-actin bound to cofilin are

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Differential metabolic markers associated with primary open-angle glaucoma and cataract in human aqueous humor

Abstract Background We aimed to gruvi golden lager identify metabolic biomarkers and investigate the metabolic alterations in relation to primary open-angle glaucoma (POAG) and cataract in human aqueous humor.Methods Sixteen POAG patients undergoing surgical treatments and 24 patients undergoing cataract surgeries were included in this case-control

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Spillover effects of RMB exchange rate among RCEP member countries: Empirical evidence from time-frequency domain approach.

This study employs time-frequency domain approach to investigate the spillover effects of renminbi (RMB) exchange rate among the Regional Comprehensive Economic Partnership (RCEP) member countries.Utilizing daily data spanning from August 2010 to August 2022, we find that currencies in the RCEP region demonstrate significant interaction, which is p

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Substantiation of Price Decisions in a Crisis Context

In this article the authors aim to address key issues regarding pricing decision substantiation in a crisis context and to create an overview of the elements that should underlie such substantiation.We can say that making price decisions hydrangea red sensation is both a science and an art, based on precise calculations and sound economic reasoning

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